|Age:||18 years or older|
|Keywords:||Urothelial Carcinoma, bladder cancer|
|Type:||Drug study, Phase 3|
This study has two study groups.
If you are in Group 1 you will receive treatment with MK- 3475. The MK-3475 will be given through your vein over 30 minutes once every 3 weeks. If you are in Group 2 you will be followed with scans without treatment. You will not receive any treatment but you will be contacted every 3 weeks with a phone call from your doctor’s office to see how you are feeling. You will also be asked to come back to the clinic every 6 weeks for a check-up for one year.
A computer will by chance assign you to one of the 2 groups in this study. This is called randomization. This is done by chance because no one knows if one study group is better or worse than the others. You will have an equal chance of being placed in either group. Prior to randomization, a sample of your tumor tissue will be sent to a laboratory to determine if it contains a protein called PD-L1. This test is required because they will help the investigators determine who will be most likely to respond to this treatment in the future. In addition, it will ensure that the 2 groups are equal. The results of the PD-L1 will not be shared with you or your physician.