Are you experiencing sciatica (leg pain), from a herniated disc?

Enter your info and the study team will contact you soon!
Your data is securely stored and only shared with the research team
Please answer a few questions to see if you may qualify.
Have questions? Please contact the study coordinator Janice Wang-Polagruto at or call (916) 915-0425
By clicking "Next", you're consenting to participate in this questionnaire. There are no right or wrong answers and everything you enter is secure.
  1. *1. What is your age?
  2. *2. What is your gender?
  3. *3. What is your height?
  4. *4. What is your weight?
  5. *5. Do you have a herniated disc in your lower back (lumbar spine)?
  6. *6. Are you experiencing leg pain from a herniated disc?
  7. *7. Are you experiencing back pain from a herniated disc?
  8. *8. Have you received any operations on your herniated disc?
  9. *9. Are you currently receiving workers compensation or involved in personal injury litigation relating to your disc?
  10. *10. Have you received any medications or therapies for lumbar disc herniation?
Logo Image
"Please consider joining this clinical research study examining the effectiveness of an investigational drug injection for leg pain."
Age: 30-70 years
Healthy Volunteers: No
Keywords: Low Back Pain, Herniated Disc, Investigational Drug, Clinical Research Study, Leg pain, Sciatica, lumbar disc herniation, radiculopathy
Type: Drug study, Phase 3
10 Participants
The goal of this clinical trial is to test if a single injection in the spinal disc works well. The investigational injection will be tested in patients with lumbar disc herniation (LDH).

Lumbar disc herniation (LDH) is very common and happens when the soft center of a spinal disc bulges out. This bulging can compress nearby nerves causing pain, numbness, or weakness in a leg.

This study is conducted at the UC Davis Spine Center. You will receive all study medication, or control injection and study evaluations at no cost, and compensation for your time is available.
This study requires

The study will take approximately 12 months. The study involves:

  • 10 study visits

  • Follow-up phone calls

In this study, you may receive the study medication or control injection. A control injection does not contain any active treatment. Please sign up to learn more.

Who can participate
  • People with a single lower back herniated disc (at L4-L5, L5-L6, or L5-S1)

  • Have associated leg pain for 6 weeks or more

Who cannot participate:

  • If you are receiving worker's compensation

  • If you have undergone lumbar surgery at the affected level

  • If you have a BMI ≥ 40

Benefits and risks of participating
You are not guaranteed any benefit by participating in the research study. Possible benefits may include decreased discomfort associated with lumbar disc herniation. Risks include back pain, pain in leg, back fatigue, skin changes near the injection site, abnormal lab values in blood tests.
$50 per study visit (10 study visits total)
Study duration and period
The study will take approximately 12 months with 10 study visits.
Recruitment period
From Sept. 1, 2018
UC Davis Spine Center
3301 C Street
Suite 1500
Sacramento, CA 95816
Janice Wang-Polagruto

Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.


Send SMS with Study Info:

SMS Sent!

Share Study Info via Email:

E-mail Preview