Collection of Tissue Samples for Cancer Research

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"Collection of samples (cancerous tissue, normal tissue, blood) and related medical information for use in cancer research"
Age:
18 to 100 years old
Gender:
Any
Healthy Volunteers:
No
Keywords:
cancer, biopsy, tumor
Type:
Procedure study, Phase 1
Investigator:
Description
The purpose of this study is to collect specimens for future research. This is not a treatment study. This research study that is being conducted by the National Cancer Institute (NCI).

Tissue samples may be obtained when surgery is performed to remove a tumor as part of treatment. You may also be asked to undergo procedures, such as biopsies, solely to provide tissue or blood specimens for this research study. Your doctor or nurse will provide you a description of these procedures or tests, the purpose of the procedures or tests and their risks. In case of biopsies or surgical procedures, a member of your medical team will discuss the specific procedure in detail with you, including the side effects and you will be asked to sign a separate consent form.

We are asking your permission to collect and store blood and/or tissue samples from obtained during one of the above mentioned procedures

We will use samples from the above procedures for our research studies. These samples will be stored for an indefinite period of time and will be used to develop laboratory tests to study the effects of various drugs on human tissues and cells, or may be grown as ‘preclinical models’ in animals such as mice to learn how tumors respond to new drugs for cancer.
This study requires
Blood tests
Biopsies
Medical information about the type of cancer, cancer drugs taken, and how your tumor responded to the cancer drugs
Who can participate?
- INCLUSION CRITERIA:

- Patients who are being evaluated and or treated for cancer at the NIH Clinical Center or at participating sites.

- Ability to understand and willingness to sign a written informed consent document indicating their willingness to have their tissue or biologic fluid specimens used for research as outlined in this protocol.

- Age greater than 18 years

EXCLUSION CRITERIA:

- Patients with invasive fungal infections

- Patients with active and/or uncontrolled infections or who are still recovering from an infection:

- Actively febrile patients with uncertain etiology of febrile episode

- All antibiotics should be completed at least 1 week (7 days) prior to collection

- No recurrence of fever or other symptoms related to infection for at least 1 week (7 days) following completion of antibiotics

- Patients with Human Immunodeficiency Virus (HIV), active or chronic hepatitis (i.e., quantifiable HBV-DNA and/or positive HbsAg, quantifiable HCV-RNA) or known history of HCV or HBV without documented resolution. Testing for hepatitis B or other infections for eligibility will be performed only if clinically indicated.

- Tumor tissue or blood collections from patients with benign tumors including desmoid tumors, carcinoma in situ, or ongoing complete disease response (CR).

- Blood Only Collections

- Blood will not be collected from patients whose disease demonstrates ongoing partial response or with ongoing (i.e., prolonged) stable disease given the poor rate of model generation from such samples.
Resources
Schedule
Study duration and period
Variable
Recruitment period
From Feb. 19, 2014
Location
UC Davis Comprehensive Cancer Center
2279 45th Street
Sacramento, CA 95817
Research Topic
Conditions:
  • Neoplasms
  • Lymphomas

Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.


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