|Age:||18 to 99 years old|
|Keywords:||COVID-19, coronavirus, coronavirus infection, novel coronavirus|
|Type:||Other study, Phase 2|
If you qualify for the study and decide to join, you will get 1 infusion every day while you are a patient in the hospital. The maximum number of infusions you will receive is 10. The infusion will be either study drug or placebo, depending on what group you are in. The infusion takes about 1 hour and will be done in the hospital. We will watch you closely for side effects during the infusion and for 1 hour after the infusion. After you are discharged from the hospital, you will not received any more infusions.
We will take one blood sample and one oropharyngeal (OP) throat swab sample from you on Days 1, 3, 5, 8, and 11 as long as you remain a patient in the hospital. You will come back to the site for study visits on Days 15 and 29. During these follow-up visits, we will ask how you are feeling and if you have been sick. We will take one blood sample and one OP swab sample at Day 15 and 29.
We will use the blood and OP swab samples for research and safety tests. OP swab samples will be tested for presence of the virus that causes COVID-19.
We will obtain some information about you from your inpatient hospital records, such as whether you are receiving oxygen or need additional help breathing and what types of other medicines you are being given as part of your clinical care. This information will help us determine how sick you are and whether you are improving.
As part of this study, we will get extra blood samples from you. We will use your coded information, leftover samples, and extra blood samples for secondary research. Secondary research is research that is not part of this study, and the research is not planned yet. This extra research will occur in the future and it will help us to understand how the study drug works and to develop new treatments and lab tests. This secondary research will not include genetic testing. When you give consent, you will be taking part in the treatment study and allowing for your samples to be used for secondary research.
Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.