MDD Study- Adults with Major Depressive Disorder
University of North Carolina at Chapel Hill
The study has not started recruiting participants.
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Please answer a few questions to see if you may qualify.
Have questions? Please contact the study coordinator Morgan Alexander at or call (919) 966-4755
By clicking "Next", you're consenting to participate in this questionnaire. There are no right or wrong answers and everything you enter is confidential.
  1. 1. Are you between the ages of 18-65?
  2. 2. Have you been diagnosed with depression?
  3. 3. Have you ever, or are you currently being treated for a neurological condition (i.e. epilepsy, migraines, etc)?
  4. 4. Are you currently taking any benzodiazepines or anticonvulsants?
    Benzodiazepines include antivan, xanax, klonopin, or valium; Anticonvulsants include trileptal, neurontin, lamictal, or depakote
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"Volunteer for research at UNC and contribute to discoveries that may improve health care for you, your family, and your community!"
Age: 18 to 65
Healthy Volunteers: No
Keywords: brain/head, depression, mental health
Type: Device
20 Participants
The purpose of this study is to investigate the effects of non-invasive transcranial alternating current stimulation (tACS) on patients with Major Depressive Disorder. Transcranial current stimulation is a technique that delivers low-intensity current to the scalp. Treatment has been well tolerated with no serious side-effects reported. This intervention is aimed at restoring normal brain activity and function which may reduce mood symptoms experienced with Major Depressive Disorder. This research investigates a promising new non-pharmacological treatment for psychiatric disorders.
This study requires
  • 1 phone screening

  • 1 screening visit

  • 8 clinic visits (includes 2 follow-up sessions)

Who can participate

You are eligible to participate if:

  • Diagnosis of Major Depressive Disorder (MDD)

  • Currently not taking benzodiazepines or anti-convulsant medications

Benefits and risks of participating
Benefits: Research is designed to benefit society by gaining new knowledge. The ability to target abnormal brain activity could lead to treatments for symptoms in patients with schizophrenia and other psychiatric conditions. There is a small chance that you may experience a reduction in the severity of your auditory hallucinations. At this time we will not offer additional treatments for people who respond well, but you may asked to be informed about future studies.

Risks: Mild tingling, burning, or itching underneath the electrodes on the scalp and/or the appearance of flashing lights. Some subjects report headaches.
$355.00 in total including a $20.00 completion bonus
Study duration and period
7 weeks
Recruitment period
From May 1, 2015 to June 30, 2020

Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.


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