Novel Treatment for Nasal Tumors

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"Help us treat nasal tumors in dogs using a new kind of therapy!"
Animal: Dogs
Healthy Pets: No
Keywords: Nasal Cancer, nasal, tumor, mass, cancer, dog, canine, nose, TAE, transarterial embolization
Type: Device
Target:
10 Participants
Investigator:
Background and purpose
Nasal tumors can cause severe nasal bleeding or discharge and difficulty breathing. These tumors often aggressively spread throughout the tissues of the nasal cavity and into the surrounding organs, including the eye and brain. Radiation therapy is the treatment of choice for nasal tumors in dogs; however, radiation therapy isn't often good for long-term control of the tumor. An another treatment option is transarterial embolization, or TAE, which involves the delivery of a mechanical “clot” to the main arteries supplying blood to the tissues of the nasal cavity with the goal of eliminating the blood supply of the tumor and decreasing tumor size.

The purposes of this study are to 1) describe TAE in dogs with naturally-occurring nasal cancer, 2) evaluate the effect that nasal TAE has on the tumor, and 3) evaluate the effect that nasal TAE has on the values measured by positron emission tomography (PET) scanning.
What happens in this study

If you agree for your dog to take part in this study, your dog will undergo:

  • Transarterial embolization (TAE)
  • A PET/CT scan. This will be repeated at 1 month post-TAE.
Pet owner responsibilities

If you choose for your dog to take part in this study, you will need to:

  • Bring dog in for all scheduled visits
  • Cover costs of the TAE and any medical costs from any complications that may occur
  • Complete owner questionnaires
Participation requirements

We are looking for dogs diagnosed with nasal cancer.

To find out if your dog can take part in this study, your dog will need a CT scan. If the CT scan demonstrates that invasion of adjacent structures is present, your dog may not be able to be enrolled and you will need to cover the costs of that CT scan.

Benefits and risks of participating
We hope that the data acquired in this study will allow us to advance the treatment of cancer in both dogs and people.
Compensation
The study will cover both of the PET/CT scans and associated anesthesia.
Resources
Schedule
Study duration and period
Your dog will be in this study for approximately 4-5 weeks.
Recruitment period
From Feb. 25, 2019
Location
UC Davis Veterinary Medical Teaching Hospital
1 Garrod Drive
Small Animal Clinic - Soft Tissue Surgery
Davis, CA 95616
Contact
Dr. William Culp

Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.


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