Stimulation to Improve Auditory Hallucinations - STILL 3
University of North Carolina at Chapel Hill

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Please answer a few questions to see if you may qualify.
Have questions? Please contact the study coordinator Kaelin Kennedy at STILL3Study@unc.edu or call (919) 962-5456
By clicking "Next", you're consenting to participate in this questionnaire. There are no right or wrong answers and everything you enter is confidential.
  1. *1. Do you currently have a diagnosis of schizophrenia or schizoaffective disorder?
  2. *2. Do you currently experience auditory hallucinations three (3) or more times per week?
  3. *3. Are you currently taking any benzodiazepines (e.g., Ativan, Klonopin) or anticonvulsants (e.g., Neurontin, Depakote)?
  4. *4. Have you ever had a serious traumatic brain injury or brain surgery, including any devices or implants?
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"A research study to test whether a low-current transcranial stimulation can reduce auditory hallucinations"
Age: 18-70
Gender:
Any
Healthy Volunteers: No
Keywords: schizophrenia, schizoaffective disorder, hallucination, Stimulation, auditory hallucination
Type: Clinical Trial
Target:
40 Participants
Investigator:
Description
The purpose of this study is to investigate the effect of transcranial alternating current stimulation (tACS) on auditory hallucinations in people with schizophrenia. Transcranial current stimulation is a non-invasive technique that delivers very low intensity current to the scalp; treatment has been well tolerated with only minor side effects such as 'tingling' during stimulation.

This intervention is aimed at restoring normal brain activity and function to reduce auditory hallucinations. This research represents a promising new non-pharmacological treatment for psychiatric disorders and our findings will serve to enhance the research community's understanding of schizophrenia.
This study requires

• 1 phone screening • 2-4 screening visits • 5 consecutive visits • 1 fifteen minute MRI scan • 8 weeks of once weekly stimulation

Who can participate

• Diagnosis of schizophrenia or schizoaffective disorder • At least 3 auditory hallucinations per week • Stable doses of medication for at least 4 weeks • Not currently taking benzodiazepine medication

Benefits and risks of participating
Benefits: Research is designed to benefit society by gaining new knowledge. The ability to target abnormal brain activity could lead to treatments for symptoms in patients with schizophrenia and other psychiatric conditions. There is a small chance that you may experience a reduction in the severity of your auditory hallucinations. At this time we will not offer additional treatments for people who respond well, but you may asked to be informed about future studies.

Risks: Mild tingling, burning, or itching underneath the electrodes on the scalp and/or the appearance of flashing lights. Some subjects report headaches.
Compensation
Participants will be paid at the end of each session and can earn up to $760.00 for completing all visits.
Resources
Schedule
Study duration and period
14-18 weeks
Recruitment period
From Nov. 1, 2017 to Jan. 1, 2020
Locations
UNC Chapel Hill
334 Emergency Room Drive
Wing C, Room 233
Chapel Hill, NC 27514
UNC STEP Clinic - Wake County
3010 Falstaff Road
Raleigh, NC 27610
Contact
Kaelin Kennedy

Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.


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