|Age:||8-14 years old|
|Keywords:||Autism spectrum disorder, anxiety|
Pre-Treatment Visits Cognitive and anxiety testing
Eye tracking task
Questionnaires about your child
Standardized neuropsychological assessments
Parent interview about your child’s development and anxiety symptoms (1-2 hours).
Treatment VisitsYour child will be randomly assigned to a treatment of either: Cognitive-Behavioral Therapy (CBT) Medication (Sertraline OR Placebo)
Post-Treatment Visits Your child will repeat the set of testing done at the beginning (MRI, eye tracking, and behavioral testing). This will be used to determine how the treatment phase impacted your child.
Boys and girls with ASD between ages 8-14 years
Has or is suspected of having an autism spectrum disorder.
Has significant anxiety symptoms (does not need to have a formal clinical diagnosis of anxiety)
IQ greater than 50 (assessed during study)
Stable medication regimen (no recent or planned significant changes).
Additional criteria may include co-morbid disorders, other medications, and other therapies. Our study team can discuss these criteria as they apply to your child.
Certain concurrent psychotherapy, social skills training, or behavioral interventions with the primary aim to treat the child's anxiety. Families will have the option of discontinuing such services to enroll in the study.
History of intolerance to sertraline or similar medications.
Current clinically significant suicidality or individuals who have engaged in suicidal behaviors within 6 months.
Major neurological disorder or medical illness that requires a prohibited episodic or chronic systemic medication or that would interfere with study participation (e.g., frequent hospitalizations, frequent school absences).
Inability to safely swallow study medication after pill swallowing education
Child and parent/caregiver who do not speak English.
Additional criteria may apply. Please contact us with any questions about the study or eligibility.
Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.