8-12 years old
Autism spectrum disorder, anxiety
Cognitive and anxiety testing
Eye tracking task
Questionnaires about your child
Standardized neuropsychological assessments
Parent interview about your child’s development and anxiety symptoms (1-2 hours).
Assessments and interview will be videotaped for scoring and reliability purposes to ensure consistency in data collection. If you agree to be videotaped, you reserve the right to review/edit the tapes.
Cognitive-Behavioral Therapy (CBT)
Medication (Sertraline & Pill Placebo), Medication log
At the end of treatment, your child will repeat the set of testing done at the beginning (MRI, eye tracking, and behavioral testing). This will be used to determine how the treatment phase impacted your child.
You will be asked to return three more times after the end assessment, at 4 week intervals. These visits will serve as check-ins to see how your child is doing after ending treatment. At the final visit, your child will do a third round of behavioral testing. This will be compared to the tests done at the end of treatment to determine whether the effects are lasting
Outpatient boys and girls with ASD between ages 8-12 years at consent.
Has a diagnosis of ASD
Has significant anxiety symptoms
IQ greater than 50 (assessed during study)
Stable medication regimen (no recent or planned significant changes).
Additional criteria may include co-morbid disorders, other medications, and other therapies. Our study team can discuss these criteria as they apply to your child.
Certain concurrent psychotherapy, social skills training, or behavioral interventions. Families will have the option of discontinuing such services to enroll in the study.
Child has history of intolerance to sertraline.
Current clinically significant suicidality or individuals who have engaged in suicidal behaviors within 6 months.
Child has a major neurological disorder or medical illness that requires a prohibited episodic or chronic systemic medication or that would interfere with study participation (e.g., frequent hospitalizations, frequent school absences).
Inability to safely swallow study medication after pill swallowing education.
Contraindications to MRI (e.g., metal in the body).
Child and parent/caregiver who do not speak English.
Additional criteria may apply. Please contact us with any questions about the study or eligibility.
Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.