moderate brain injury, severe brain injury
• Blood samples will be collected Days 1, 3, 5, 15, 30, 90, and 180 after your injury. Total amount of blood collected will be approximately two tablespoons each time. • Telephone outcome questionnaires will be conducted at 1, 3, 6, 12, and 24 months after your injury. This will take approximately 45 minutes of your time
Data will be obtained both from the activities described here and also from data generated during your standard clinical care
Inclusion Criteria: • Acute Traumatic Brain Injury (TBI) • Age 12-100 are eligible • GCS 3-12 • Hemorrhagic contusional injuries to frontal and/or temporal lobes. • Polytrauma including long bone fractures, blunt trauma, abdominal trauma or similar will be allowed. • Penetrating TBI if cEEG is feasible and survival for 2 years is feasible, recognizing that MRI may not be feasible with some forms of penetrating trauma
Exclusion Criteria: • Ages 11 years or younger • Patients with diffuse axonal injury in the absence of hemorrhagic contusions or skull fracture, and isolated epidural hemorrhages that improve after evacuation. • Inability to undergo MRI within 2 weeks of injury (bullet, metal implant, and pacemaker) studies in the acute and chronic setting. • Pregnancy • Inability to undergo MRI within 2 weeks of injury • Pre-existing Neurodegenerative Disorders • Pre-existing seizures • Pre-existing dementia • Isolated anoxic brain injury • Incarceration present or pending
Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.