Surgical technique to place urethral stents in dogs with prostate, bladder and/or urethra tumors

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"Help us study a new technique to place urethral stents in dogs with prostate, bladder, and/or urethra tumors!"
Animal: Dogs
Age: None specified
Healthy Pets: No
Keywords: lower urinary tract neoplasia, cancer, tumor, urethral stent, transrectal ultrasound, TRUS, bladder cancer, prostate cancer, urethral cancer, urethral blockage
Type: Device / Surgical Technique
12 Participants
Background and purpose
Cancer resulting in obstruction of the lower urinary tract of dogs is most commonly found in the prostate, urinary bladder and urethra (tube responsible for draining urine out of the body). Unfortunately, cancer of the lower urinary tract often results in complete blockage of the urethra, causing a patient to be unable to pass urine. The inability to urinate is a life-threatening emergency.

The placement of urethral stents is generally performed with fluoroscopic-guidance (use of “real-time” x-rays). While fluoroscopy is useful for stent placement, there may be other techniques that could be considered. Traditionally, ultrasonographic assessment of tumor size and location has been performed by transabdominal ultrasound (where the ultrasound probe is placed on the abdominal wall to allow for visualization of organs within the abdomen), but this method can be inaccurate. The use of transrectal ultrasound (where an ultrasound probe is placed into the rectum) circumvents these previously discussed problems, and therefore, the purpose of this study is to evaluate this technique for efficacy.
What happens in this study
  • Transrectal ultrasound (TRUS), fluoroscopy (real time “x-rays”) and urethral stent placement under anesthesia
  • Completion of questionnaires pre-stent placement, 2-weeks post-stent placement and 3-months post-stent placement to assess outcome
Pet owner responsibilities

You will be responsible for covering equipment costs associated with the urethral stent placement and any complications of the procedure, keeping all scheduled appointments and completing a questionnaire pre-stent placement, 2 weeks after stent placement and 3 months after stent placement.

Participation requirements

We are looking for dogs with a diagnosis of prostatic, bladder or urethral cancer and secondary urethral obstruction for whom a stent is being offered/recommended and believed to be clinically beneficial.

Benefits and risks of participating
Benefits of enrolling in this study include financial support for the ultrasound, stent placement and anesthesia. We hope that the data acquired in this study will allow us to advance the treatment of cancer in both pets and people.
The study will cover the fluoroscopy, ultrasound, and anesthesia.
PDF Docs
Clinical Trial Informational Flyer
Study duration and period
Dogs enrolled in this study will only need to have diagnostics related to the study performed at the same time as urethral stent placement. Owners will be responsible for completing a questionnaire pre-stent placement, 2 weeks after stent placement and 3 months after stent placement.
Recruitment period
From Sept. 8, 2016 to Sept. 8, 2019
UC Davis Veterinary Medical Teaching Hospital
1 Garrod Drive
Small Animal Clinic - Soft Tissue Surgery
Davis, CA 95616
Dr. Bill Culp

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