The BRAIN Study

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Please answer a few questions to see if you may qualify.
Have questions? Please contact the study coordinator at or call (916) 249-8866
By clicking "Next", you're consenting to participate in this questionnaire. There are no right or wrong answers and everything you enter is confidential.
  1. *1. How old is your child?
  2. *2. What is your child's gender?
  3. *3. Is your child in an environment where English is spoken?
  4. *4. Which of the following best describes your child?
  5. 5. What is your child's first name? (Optional)
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"Studying different patterns of brain development in children"
Age: 24- 42 months
Healthy Volunteers: Yes
Keywords: Children, Autism Spectrum disorder (ASD)
Type: Other
Autism is a very complex disorder, and it is likely that various subtypes exist. For over 10 years, investigators at the MIND Institute have been working to define different subtypes or “phenotypes” of autism in order to develop the best treatments for each type.

In our previous work, we have found that about 15% of boys with ASD have a large brain form of autism. Besides a big brain, we have found that these kids have a different behavioral profile than other kids with ASD.

The primary goal of this project is to further study the large brain ASD children compared to other children with and without ASD.
This study requires

You and your child will be scheduled for 3-4 visits during the first year. We will also ask you to return for follow-up visits one and two years after your first visit to see how your child has changed over time.

Study visits include:

Behavioral & psychological assessments - looking at development, autism symptoms, and language

Medical exam - includes medical history and a brief physical exam

Blood draw - blood samples from child and one or both biological parents with our pediatric phlebotomist

MRI scan during natural sleep(without sedation) - looking at brain structure

EEG (electroencephalogram) - looking at brain activity

Questionnaires - evaluating various aspects of your child's behavior

Who can participate

Inclusion criteria for all children:

-Age 24 to 42 months

-Diagnosis of autism OR is typically developing

-No contraindications for MRI (e.g., metal in body)

-Weigh at least 20 pounds

-Family speaks and understands English

Exclusion criteria for all children:

-Fragile health condition that would prevent the child from participating in the study

-Presence of any metal or electromagnetic implants that would prevent MRI testing

Additional criteria may apply.

Benefits and risks of participating
We cannot promise any benefits to you or others from your taking part in this research. A brief summary of information about your child’s psychological functioning will be available to you and may be helpful in developing educational and behavioral interventions. The information gained from the MRI scan may be beneficial for future treatment and diagnosis of autism. You will receive a copy of the MRI scan for your medical records. The information gained from the study may be beneficial for future treatments and diagnosis of neurodevelopmental disorders. The benefits of research using specimens include learning more about what causes diseases, how to prevent them, how to treat them, and how to cure them.

This is a low risk study with minimally invasive procedures.
The study will compensate $50 for each of the completed visits that make up the study. Your child will choose a child-appropriate gift from a grab-bag at the end of each visit. Parking and mileage reimbursement will be provided. Compensation is based on visit and not on the ability to complete tasks during that visit. You will still receive compensation even if you only participate in part of the study.
Study duration and period
You and your child will be in this study for approximately one to two months during the first year visit (typically 3-4 visits). You will be asked to return for follow-up visits one and two years after your first visit.
Recruitment period
From Dec. 1, 2017
UC Davis MIND Institute
2825 50th Street
Sacramento, CA 95817

Have any questions or want to learn more? Leave your contact details below and the research team will reach out to you.


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