Tranexamic acid (promotes blood clotting) or placebo and direct pressure for treatment of nosebleeds in Emergency Department

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"Can tranexamic acid reduce the duration of a nosebleed?"
Age: 18 to 100 years old
Healthy Volunteers: No
Keywords: nosebleed
Type: Drug study
This study will be evaluating the benefits of topical intranasal tranexamic acid (promotes blood clotting) for patients with epistaxis (nosebleeds). Tranexamic acid is not currently approved by the FDA for the treatment of nosebleeds
This study requires

Treatment for nosebleed in ER Treatment with Tranexamic acid and direct pressure or placebo and direct pressure Follow up phone call

Who can participate

Inclusion Criteria:

  • Diagnosed with anterior epistaxis

Exclusion Criteria:

  • Unable to consent, do not have a valid telephone number, pregnant women, prisoners, cognitively impaired individuals, diagnosis of posterior epistaxis, major trauma, bleeding disorder (such as thrombocytopenia or hemophilia), hemodynamically unstable, or had a known hypersensitivity to study medication
Study duration and period
Treatment period: 30 minutes Follow up call: within one week
Recruitment period
From Feb. 4, 2016
Department of Emergency Medicine
4150 V Street
Suite 2100
Sacramento, CA 95817
Research Topic
  • Epistaxis

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