Using a new technique to shrink liver tumors in dogs

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"Help us learn more about this new technique that could shrink liver tumors in dogs!"
Animal: Dogs
Age: None specified
Sex:
Any
Healthy Pets: No
Keywords: liver tumor, tumor, cancer, liver neoplasia, TAE, transarterial chemoembolization, TACE, transarterial embolization, hepatocellular carcinoma
Type: Device / Surgical Technique
Target:
24 Participants
Investigator:
Background and purpose
When liver tumors in dogs cannot be removed with surgery, treatment options are limited or non-existent. In humans, one of the standard treatments for those cases is transarterial embolization (TAE), which eliminates the blood supply of the tumor and may decrease tumor size. Therefore, the objectives of this study are to 1) describe the procedure of TAE in a group of dogs with naturally-occurring liver cancer, and 2) evaluate the effect that liver TAE has on clinical signs and the size of the tumor.
What happens in this study

If you agree to have your dog participate in this study, the following procedures will occur:

  • An abdominal ultrasound scan
  • CT scan, PET scan and TAE while under anesthesia
  • A second ultrasound scan, CT scan and PET scan approximately 4 weeks post-TAE
  • Hospitalization for 1-2 days post treatment pending response to treatment
  • Completion of questionnaires
Pet owner responsibilities

If you allow your dog to participate in this study, you will be responsible for keeping all scheduled appointments, completing several questionnaires, and covering costs associated with the TAE procedure and any complications that may occur as part of that procedure.

Participation requirements

We are looking for dogs diagnosed with liver cancer that has been determined to be non-removable or in a location with great surgical risk.

Benefits and risks of participating
We hope that the data acquired in this study will allow us to advance the treatment of cancer in both pets and people.
Compensation
The study will cover costs associated with the ultrasounds, CT scans, PET scans and anesthesia.
Resources
PDF Docs
Clinical Trial Informational Flyer
Schedule
Study duration and period
Dogs will be placed under anesthesia and CT and TACE will be performed under the same anesthesia. Four weeks later, your dog will need to be returned for a repeat CT scan.
Recruitment period
From Sept. 22, 2016 to Sept. 22, 2019
Location
UC Davis Veterinary Medical Teaching Hospital
1 Garrod Drive
Small Animal Clinic - Soft Tissue Surgery
Davis, CA 95616
Contact
Dr. Bill Culp

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