[Walnut Creek, CA] Alzheimer's Disease Neuroimaging Initiative study

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"Actively recruiting those with Mild Cognitive Impairment or Early Alzheimer's disease"
55 Years to 90 Years
Healthy Volunteers:
Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD)
Observational, Imaging Study
2000 Participants
The overall goal of this study is to discover and study the clinical, cognitive, imaging, genetic and biochemical biomarkers as the Alzheimer's disease (AD) evolves from normal aging through very mild symptoms, to mild cognitive impairment (MCI), to dementia.

This is a large public/private collaboration between academia and industry to study biomarkers of AD. Approximately 1070 - 2000 participants will be enrolled in the United States and Canada. The study has many important scientific implications: understanding biology of AD, identifying various markers, and helping develop the most effective clinical trials.

This study does not involve any treatments. Participants will need to be 55 - 90 years.
This study requires

Participants will undergo multiple clinical and cognitive assessments over time. These may include computerized cognitive tests, blood biomarker and genetic tests, imaging scans and cerebral spinal fluid (CSF) collection for up to 5 years. A study partner who has frequent contact with the participant and is available to accompany the participant to all clinic visits for the duration of the study is required.

Who can participate

We invite individuals with subjective memory complaints. If you are experiencing any abnormal signs such as these below, you may be eligible for this study.

  1. Memory loss that disrupts daily life
  2. Challenges in planning or solving problems
  3. Difficulty completing familiar tasks
  4. Confusion with time and place
  5. Trouble understanding visual images and spatial relationships
  6. New problems with words in speaking or writing
  7. Misplacing things and losing the ability to retrace steps
  8. Decreased or poor judgment
  9. Withdrawal from work or social activities
  10. Changes in mood and personality
Benefits and risks of participating
We hope the knowledge gained will be beneficial to society in improving our understanding of risk for cognitive decline in older individuals. The data from this research study will be used in the development of future research studies that will focus on the treatment of AD at an early stage.
Mild Cognitive Impairment (MCI) participants will receive total compensation of up to $1,525.

Early Alzheimer's disease (AD) participants will receive total compensation of up to $1,575.

Participants will also receive a $50 gift card annually beginning at the 1st year anniversary of participating in this study.
PDF Docs
Informed Consent Document
Study duration and period
This is a study that requires yearly visits and an online computer test. Total time commitment for participation is between 3-5 years.
UC Davis Alzheimer's Disease Center
100 North Wiget Lane
Suite 150
Walnut Creek, CA 94598
Hongzheng Zhang

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