UC Davis Health Clinical Studies

A Study of Outpatient Cervical Preparation to Reduce Induction Duration in Pregnant Women

Volunteer for research at UC Davis and contribute to discoveries that may improve health care for you, your family, and your community!

This study is to compare 2 groups in nulliparous women undergoing cervical ripening for induction of labor. The study hypothesis is that outpatient cervical preparation with a foley catheter can reduce the induction of labor (IOL) time interval from admission to delivery by 50%. A 30 ml transcervical foley catheter is a safe mode of cervical preparation in the outpatient setting, as concluded in Diederen et al, Sciscinoe et al, and Kelly et al. Findings from studies on nulliparous, term, singleton vertex (NTSV) showed patients can be applied to a wide variety of maternity unit sizes as discussed by Main et al. No previous study has evaluated the effectiveness of outpatient cervical preparation in the NTSV population by PUBMED search. Further, no previous study has assessed patient satisfaction cervical preparation in the outpatient setting and no previous study has evaluated whether outpatient cervical preparation has an impact on the length of stay and cost of hospitalization. This study will explore these important questions with the goal of improving current practices in labor induction to be more patient-centered, pragmatic, and cost-effective.

Other study
Female, age 18 years or older

Need Emergency Contraception? Participate in a research study.

We want to find out which morning-after pill is most effective in women who weigh 176 pounds or more

This study aims to find out which morning-after pill is most effective in women weighing 176 pounds or more. If you had unprotected sexual intercourse and are looking for birth control options, consider participating. Emergency contraception, also “the morning-after pill" or "plan b”, can prevent pregnancy after unprotected sexual intercourse. Unprotected intercourse includes no contraceptive used, condom breakage, and other barrier contraceptive method failures. This clinical study happens at the UC Davis Department of Obstetrics and Gynecology. All participants will receive FDA-approved emergency contraception and specialty care at no cost. Compensation for your time is available.

Drug study, Phase 4
Female, age 18 to 40 years old

Have heavy menstrual bleeding? Participate in a research study to test an intrauterine device (IUD) treatment.

We're evaluating if an IUD is safe and effective in helping women with heavy periods

We're inviting women with heavy menstrual bleeding who are not interested in being pregnant in the next 10 months. This goal of this study is to see if an intrauterine device (IUD) is safe and effective in women with heavy menstrual bleeding. This study will use an IUD that is already on the market in the United States and approved by the FDA, called Liletta®. An IUD is a device placed in the uterus to prevent pregnancy. We want to know if an IUD can be a safe and effective treatment for women with heavy menstrual bleeding. This clinical research study happens at the UC Davis Department of Obstetrics and Gynecology. You will receive the Liletta® IUD and specialty care at no cost, and compensation for your time is available.

Device study, Phase 3
Female, age 18 to 50 years old

Women needed to help us understand what happens when a birth control pill is taken late or a whole day is skipped

You may be eligible to help researchers learn more about the most effective way to use estrogen-free birth control pills!

The purpose of this clinical research study is to understand the effect of a delayed or missed birth control pill. We know that birth control pills are most effective when taken at the same time every day. This study will help us understand more about what happens to the cervical mucus and the ovaries when a progestin-only pill (POP) is taken late or a whole day is skipped. The pill used in this study is Norgestrel, a progestin-only pill (POP). This POP has been marketed in the United States in the past but is not currently approved for use so it is considered experimental. If you're currently not taking a hormonal contraceptive, are unable to become pregnant, or willing to refrain from sexual activity during the course of the study you may be eligible. This clinical research study is conducted at the UC Davis Department of Obstetrics and Gynecology. You will receive all study medication and study evaluations at no cost, and compensation for your time is available.

Drug study, Phase 2
Female, age 18 to 35 years old

Join a research study of a potential new form of birth control

Help us understand if an investigational vaginal ring is safe and effective in preventing pregnancy

This clinical trial will study the efficacy, cycle control, and safety of an investigational contraceptive vaginal ring over 12 months. The vaginal ring that will be used in this study is experimental and being developed as a possible new method of birth control. The ring in this study is used for three months before it is changed. The ring is made of silicone rubber and contains two hormones. One of the hormones is a progestin called Nestorone. The other hormone is an estrogen called estradiol. This estrogen is the same estrogen made in a woman's body. The vaginal ring releases these hormones into your body. The hormones are intended to keep women from releasing an egg so they do not get pregnant. Birth control pills work the same way. To take part in this study, you must be willing to engage in at least one act of heterosexual intercourse per month. You also must not be using another method of birth control to prevent pregnancy while you are enrolled onto this study.

Drug study, Phase 2
Female, age 18 to 35 years old