UC Davis Health Clinical Studies

The role of the subthalamic nucleus (SBN) in perceptual decision-making in humans

Help us understand how electrical signals in the brain translate to the making of decisions

The purpose of this research is to help us understand how the brain makes decisions. Several mental diseases, such as disorders of addiction, are due to problems with the way people make decisions. These diseases are very common. When these mental diseases are severe, sometimes medications are no longer effective. In these difficult cases, Deep Brain Stimulation (DBS) surgery may be an option. However, until we understand how the electrical signals in the brain translate to the making of decisions, we cannot design surgeries to treat these patients. Therefore, this study will help us understand the specific ways the brain makes certain types of decisions. We hope that this research will help us develop new treatments for people with mental diseases

Any, age 18-100

A Family-Focused Intervention for Asian American Male Smokers

Can a family-focused intervention promote smoking cessation in Chinese and Vietnamese male smokers?

This project proposes two aims. The first aim is to evaluate the efficacy of a family-focused intervention in promoting smoking cessation in Chinese and Vietnamese male smokers. Half of the participants will be assigned to the proposed intervention, and the remaining half will be assigned to an attention-control condition where they will receive education on healthy eating and physical activity. The second aim is to explore mediators to identify key psychosocial and behavioral processes that underlie how the intervention affects the processes of quitting and maintaining abstinence in Chinese and Vietnamese smokers.

Behavioral study
Male, age 18 to 100 years old

The GAIN Study

Girls with Autism - Imaging in Neurodevelopment

The GAIN Study started several years ago to bring more girls into research. Boys are diagnosed with autism about 4-5 times more often than girls. Because of this, girls are frequently excluded from autism research studies altogether. We hope to identify differences between boys and girls in order to guide more directed treatments and intervention. Participation will involve a variety of testing methods, including looking at your child’s behavior (through questionnaires and on-site assessments, biology (through a brief medical exam and blood draws on child and parents) and brain (through a nighttime MRI). There will be 2-3 visits scheduled over a 2 month period for the first year, and we would like to track your child’s development over three years. We are currently enrolling both girls with autism and without autism in order to understand how girls and boys with autism may differ.

Female, age 2-3.5