UC Davis Health Clinical Studies

Metabolic Effects of Sugar and Aspartame

What are the effects of consuming sugar- and aspartame-sweetened beverages with standardized diets?

We hope to learn more about the effects of consuming sugar- and aspartame-sweetened beverages with meals in a situation in which we know exactly what the other meal components consists of. Therefore, throughout the first 6 weeks of the study we will provide the participants with the sweetened beverages and the meals that they will consume with the beverages. This will allow us to study if consumption of sugar-sweetened beverages has effects on your blood triglyceride and cholesterol concentrations and your body’s sensitivity to the hormone insulin without having to account for the other components in your usual diet. We also hope to learn more about the effects of consuming sugar-sweetened beverages with the meals people usually consume. Therefore during the last 4 weeks of the study participants will consume the beverages we provide with their normal meals.

Other study
Any, age 18 to 40 years old

Study of the Relationship Between Body Composition, Insulin Resistance and HDL Levels

HDL Study

Patients having chronic kidney disease have lower than expected level of HDL the "good cholesterol". Having a low HDL (High Density lipoprotein) cholesterol level is associated with diabetes and obesity, and is a risk factor for cardiovascular disease (heart attack or stroke). Dr. George Kaysen is a world renowned expert in the area of lipid metabolism, inflammation, and vascular disease specifically in patients having kidney disease. He is conducting this research to find the causes. We currently need hemodialysis, and chronic kidney disease patients (CKD3b and CKD4) to enroll.

Kidney Disease
Any, age 18-75