UC Davis Health Clinical Studies

The BRAIN Study

Studying different patterns of brain development in children

Autism is a very complex disorder, and it is likely that various subtypes exist. For over 10 years, investigators at the MIND Institute have been trying to define different subtypes or “phenotypes” of autism in order to develop the best treatments for each type. As part of this effort, we have been examining the brains of children with autism and age matched typically developing kids to see if there are different patterns of development and organization. In our previous work, we have found that about 15% of boys with ASD have a large brain form of autism. Besides a big brain, we have found that these kids have a different behavioral profile than other kids with ASD. On average, they showed fewer gains in IQ and language by age 5. However, some children with ASD and a big brain showed gains instead. The primary goal of this project is to further study the large brain ASD children compared to other children with and without ASD.

Any, age 24- 42 months