UC Davis Health Clinical Studies

A Study of the Experimental Combination of Cabozantinib and Nivolumab For Advanced Endometrial Cancer

Volunteer for research at UC Davis and contribute to discoveries that may improve health care for you, your family, and your community!

This study will test how well experimental cabozantinib and nivolumab work. They will be given to patients with endometrial cancer that has come back or spread to other places in the body. Cabozantinib may stop tumor cells from growing. It does this by blocking enzymes needed for cell growth. Nivolumab is a type monoclonal antibody. It may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib and nivolumab together is considered experimental. The combination may work better in treating endometrial cancer.

Drug study, Phase 2
Female, age 18 years or older

Have heavy menstrual bleeding? Participate in a research study to test an intrauterine device (IUD) treatment.

We're evaluating if an IUD is safe and effective in helping women with heavy periods

We're inviting women with heavy menstrual bleeding who are not interested in being pregnant in the next 10 months. This goal of this study is to see if an intrauterine device (IUD) is safe and effective in women with heavy menstrual bleeding. This study will use an IUD that is already on the market in the United States and approved by the FDA, called Liletta®. An IUD is a device placed in the uterus to prevent pregnancy. We want to know if an IUD can be a safe and effective treatment for women with heavy menstrual bleeding. This clinical research study happens at the UC Davis Department of Obstetrics and Gynecology. You will receive the Liletta® IUD and specialty care at no cost, and compensation for your time is available.

Device study, Phase 3
Female, age 18 to 50 years old

Koa Family: California's Obesity Prevention Project

This study hopes to learn if a new whole health program improves the health of low-income mothers.

The purpose of this study is to learn if a new whole health program improves the health of low-income mothers. To be eligible for this study, you must be a woman between the ages of 18 and 47. You must be comfortable speaking and reading English and be a mother (or caregiver) whose youngest child is between the ages of 3 and 17. You also must live in a low-income household (at or below 185% of the Federal Poverty Level), live in the Mack Road neighborhood of Sacramento or the City of Woodland, and have a cell phone that can receive text messages.

Behavioral study
Female, age 18 to 47 years old

Women needed to help us understand what happens when a birth control pill is taken late or a whole day is skipped

You may be eligible to help researchers learn more about the most effective way to use estrogen-free birth control pills!

The purpose of this clinical research study is to understand the effect of a delayed or missed birth control pill. We know that birth control pills are most effective when taken at the same time every day. This study will help us understand more about what happens to the cervical mucus and the ovaries when a progestin-only pill (POP) is taken late or a whole day is skipped. The pill used in this study is Norgestrel, a progestin-only pill (POP). This POP has been marketed in the United States in the past but is not currently approved for use so it is considered experimental. If you're currently not taking a hormonal contraceptive, are unable to become pregnant, or willing to refrain from sexual activity during the course of the study you may be eligible. This clinical research study is conducted at the UC Davis Department of Obstetrics and Gynecology. You will receive all study medication and study evaluations at no cost, and compensation for your time is available.

Drug study, Phase 2
Female, age 18 to 35 years old
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