UC Davis Health Clinical Studies

Improve your well-being and try a self-experimentation tool

Help us understand how self-experimentation tools can be designed to improve health and well being

Ever wonder which healthy activities are worth doing for you personally? Healthy behaviors are not one-size-fits-all. This study will test a self-guided tool called Study of Me. The tool guides you through an 30-day 'self-experiment' to figure out if a healthy activity works for you and is therefore worth doing. It uses simple self-administered healthy activity (i.e., exercise, meditation) and will be tested to see if it improves psychological well-being (i.e., happiness, stress, and focus). The purpose of this study is to evaluate the tool's design and usefulness.

At-home study
Any, age 18+

Study on Language Development in Young Adults with Fragile X Syndrome

The goal of the study is to learn more about how certain abilities (e.g. memory), certain types of experiences (e.g. interactions with family), and biology affect language abilities in adulthood for both males and females with fragile X syndrome. We are also interested in understanding how these factors and language/literacy skills affect the abilities of these young adults to function independently. Such information will help us suggest ways to improve instruction, therapy, and support to help youth fragile X to successfully transition from school to the demands of adult life.

Any, age in, entering, or just out of last year of HS

A Study Evaluating Behavioral Intervention in those at risk for Alzheimer’s Dementia

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Older adults with memory changes may eventually experience difficulty with activities of daily living (such as managing finances). This study will test an intervention for older adults who are experiencing concerns with thinking ability but do not have difficulty with managing activities of daily living. The goal of this intervention is to increase skills using a calendar system, goal setting and task list system, and organizational strategies. This intervention encourages engagement in healthy lifestyle activities such as physical exercise, intellectual stimulation, and positive emotional functioning to further promote brain health. Participants may have increased engagement in brain health activities and improved compensation strategies. All participants will have a chance to complete the intervention.

Behavioral study
Any, age 65 years or older

The Staged Treatment in Early Psychosis Study

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This study will investigate the most effective way of treating young people at risk of developing a psychotic disorder. We do not yet know what the most effective type of treatment is or the best sequence of treatments. We would like to test the effect of a sequential treatment approach for at-risk young people. This means giving them a sequence of three treatments, depending on whether the young people have a good response to each stage of treatment. The study will measure whether or not the treatment sequence was effective by: -whether the treatments improved functioning levels and psychiatric symptoms -whether or not they prevent or delay some young people transitioning to psychosis -whether they help diminish some young people’s at-risk status. The results of this study will assist with providing the best possible care in the future for young people who may be at risk of developing a psychotic disorder. It may also help us understand why some people’s symptoms and functioning get worse over time and why other people’s improve. Medications, drugs and devices have to be approved for use by the FDA. Fluoxetine is approved by the US Food and Drug Administration to treat depression. However, it is not approved to treat risk for psychosis. Therefore, its use in this study is considered to be experimental. This study will help determine if fluoxetine is an effective treatment for risk for psychosis. The research has been initiated by the study doctor, Cameron Carter, and is funded by a research grant from the US National Institute of Health (NIH).

Behavioral study, Phase 3
Any, age 12 to 25 years old