UC Davis Health Clinical Studies

The Walnut Study: Measuring the Changes in Gut Microbiota (bacteria) and Cardiometabolic Biomarkers (cholesterol)

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This study will test if eating walnuts will cause any changes in your gut microbiota (bacteria) or blood lipid profiles (cholesterol). We believe that eating walnuts will cause changes in the composition and metabolic activity of the gut microbiota. This can be measured in fecal (stool) samples. We believe that eating walnuts will improve blood lipid profiles and other markers of cardiometabolic health. This is measured in blood and urine samples, and compared to control diet without nuts.

Other study
Any, age 20 to 65 years old

Physiology and Treatment Response in Gastroesophageal Reflux Disease (GERD)

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You are invited to participate in a research study. The purpose of this research is to better understand the relationship between: - gastroesophageal reflux disease (GERD) symptoms, - physiology (e.g., heart rate and the amount of sweat produced by the skin), and - response to treatment with amitriptyline. Amitriptyline is an FDA-approved medication for depression. In low doses, it can be helpful for treating nerve pain. You are invited to be in this study because you have GERD-related symptoms with a hypersensitive esophagus.

Drug study
Any, age 24 to 64 years old

The Digital Memory Notebook: Training to Improve Everyday Functioning in Older Adults with Mild Cognitive Impairment

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We invite you to take part in a research study because you are an adult over the age of 60. We invite individuals with personal concerns regarding: -memory -thinking abilities and/or -mild difficulties with thinking and remembering. The purpose of this study is to train older adults who are at risk for memory and thinking problems. We will train then to use a tablet-based application (app) . The app is called the Digital Memory Notebook (DMN) to support everyday functioning and independence.

Behavioral study
Any, age 60 years or older

A Study of Outcomes in Patients With Complex Trauma and Significant Injuries

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You are being invited to join a research study. This study is funded by the Department of Defense (DoD). The purpose is to gain a better understanding of patient outcomes after significant injury. To do so, the study team will examine and compare characteristics across patient populations (i.e. with different injuries). Some of the patient characteristics we will be looking at will be found in your medical record. Others will include information we collect from left over (remnant) blood samples.

Other Study
Any, age 18 years or older

A Study of the Effect on Analgesics on Post-Surgical Patients

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The opioid epidemic is one of the most pressing healthcare problems in the United States. Opioid use and misuse could lead to potential overdose and potential loss of life. Laws have been paseed to limit the use of opioid-based pain medications. Additionally, the American Society of Metabolic and Bariatric Surgery (ASMBS) has initiated the BSTOP (Bariatric Surgery Targeting Opioid Prescriptions) program. The goal is to reduce narcotic based pain control measures after surgery.

Drug study
Female, age 35 to 65 years old
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