UC Davis Health Clinical Studies

Telehealth study about a parent-implemented language test for individuals with Autism Spectrum Disorder

Estudio de telesalud sobre una prueba de lenguaje aplicada por los padres en el hogar para personas con Trastorno del Espectro Autista

We are now recruiting parents along with their sons/daughters with ASD for a new study! The study aims to teach parents to administer a spoken language test to their sons/daughters in their homes via telecommunication technology (i.e. Skype). We also will be adapting the language test for use with Spanish-speaking families. Therefore, we are recruiting both families who primarily speak Spanish as well as families who primarily speak English with their children. Estamos reclutando padres junto con sus hijos/as con TEA para un nuevo estudio! El objetivo del estudio es enseñar a padres a dar una prueba de lenguaje a sus hijos/hijas en sus hogares a través de las tecnologías de telecomunicaciones (ej., Skype). También adaptaremos la prueba al español. Por lo tanto, estamos reclutando tanto a familias que hablen principalmente inglés en casa con sus hijos como a familias que hablen principalmente español con sus hijos.

outcome measures/ medidas de resultado
Any, age 6 to 23

Improve your well-being and try a self-experimentation tool

Help us understand how self-experimentation tools can be designed to improve health and well being

Ever wonder which healthy activities are worth doing for you personally? Healthy behaviors are not one-size-fits-all. This study will test a self-guided tool called Study of Me. The tool guides you through an 30-day 'self-experiment' to figure out if a healthy activity works for you and is therefore worth doing. It uses simple self-administered healthy activity (i.e., exercise, meditation) and will be tested to see if it improves psychological well-being (i.e., happiness, stress, and focus). The purpose of this study is to evaluate the tool's design and usefulness.

At-home study
Any, age 18+

Study on Language Development in Young Adults with Fragile X Syndrome

The goal of the study is to learn more about how certain abilities (e.g. memory), certain types of experiences (e.g. interactions with family), and biology affect language abilities in adulthood for both males and females with fragile X syndrome. We are also interested in understanding how these factors and language/literacy skills affect the abilities of these young adults to function independently. Such information will help us suggest ways to improve instruction, therapy, and support to help youth fragile X to successfully transition from school to the demands of adult life.

Behavioral
Any, age in, entering, or just out of last year of HS

The BRAIN Study

Studying different patterns of brain development in children

Autism is a very complex disorder, and it is likely that various subtypes exist. For over 10 years, investigators at the MIND Institute have been trying to define different subtypes or “phenotypes” of autism in order to develop the best treatments for each type. As part of this effort, we have been examining the brains of children with autism and age matched typically developing kids to see if there are different patterns of development and organization. In our previous work, we have found that about 15% of boys with ASD have a large brain form of autism. Besides a big brain, we have found that these kids have a different behavioral profile than other kids with ASD. On average, they showed fewer gains in IQ and language by age 5. However, some children with ASD and a big brain showed gains instead. The primary goal of this project is to further study the large brain ASD children compared to other children with and without ASD.

Other
Any, age 24- 42 months

Study of anxiety treatments in Autism Spectrum Disorder (ASD)

How can therapy or medication better alleviate symptoms of anxiety and/or autism?

We hope to learn more about anxiety as it uniquely manifests in autism spectrum disorder (ASD) and determine how best to alleviate anxiety in children with autism. Forty to eighty percent of children and preadolescents with autism spectrum disorder (ASD) exhibit clinically significant anxiety symptoms, which are associated with increased social deficits, depression, irritability, and stereotyped and self-injurious behaviors. While it is clear that anxiety symptoms represent a substantial problem for those with ASD, important issues that could inform treatment remain unresolved. We seek to better characterize anxiety in autism and determine whether therapy or medication can better alleviate symptoms of anxiety and/or autism.

Other
Any, age 8-14 years old

A Family-Focused Intervention for Asian American Male Smokers

Can a family-focused intervention promote smoking cessation in Chinese and Vietnamese male smokers?

This project proposes two aims. The first aim is to evaluate the efficacy of a family-focused intervention in promoting smoking cessation in Chinese and Vietnamese male smokers. Half of the participants will be assigned to the proposed intervention, and the remaining half will be assigned to an attention-control condition where they will receive education on healthy eating and physical activity. The second aim is to explore mediators to identify key psychosocial and behavioral processes that underlie how the intervention affects the processes of quitting and maintaining abstinence in Chinese and Vietnamese smokers.

Behavioral study
Male, age 18 to 100 years old

The GAIN Study

Girls with Autism - Imaging in Neurodevelopment

The GAIN Study started several years ago to bring more girls into research. Boys are diagnosed with autism about 4-5 times more often than girls. Because of this, girls are frequently excluded from autism research studies altogether. We hope to identify differences between boys and girls in order to guide more directed treatments and intervention. Participation will involve a variety of testing methods, including looking at your child’s behavior (through questionnaires and on-site assessments, biology (through a brief medical exam and blood draws on child and parents) and brain (through a nighttime MRI). There will be 2-3 visits scheduled over a 2 month period for the first year, and we would like to track your child’s development over three years. We are currently enrolling both girls with autism and without autism in order to understand how girls and boys with autism may differ.

Observational
Female, age 2-3.5