UC Davis Health Clinical Studies

A Study of Snacks and Satiety (feeling fed)

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There are still many questions about how we control our appetite and overall food intake. One theory is that fluctuations in blood glucose tell the brain to eat or stop eating. Another theory suggests that certain amino acids in proteins we eat provide ‘stop’ and ‘go’ signals for eating. Many nutrition studies point to high protein or high carbohydrate foods to influence appetite. However, it is not clear if eating snacks, high or low in protein or carbohydrate, can actually affect appetite. We are doing this study to determine if snacks affect appetite and overall food intake. The snacks being used in this study are either almonds (higher in proteins) or a cereal blend (higher in carbohydrates).

Other study
Female, age 18 to 45 years old

Telehealth study about a parent-implemented language test for individuals with Autism Spectrum Disorder

Estudio de telesalud sobre una prueba de lenguaje aplicada por los padres en el hogar para personas con Trastorno del Espectro Autista

We are now recruiting parents along with their sons/daughters with ASD for a new study! The study aims to teach parents to administer a spoken language test to their sons/daughters in their homes via telecommunication technology (i.e. Skype). We also will be adapting the language test for use with Spanish-speaking families. Therefore, we are recruiting both families who primarily speak Spanish as well as families who primarily speak English with their children. Estamos reclutando padres junto con sus hijos/as con TEA para un nuevo estudio! El objetivo del estudio es enseñar a padres a dar una prueba de lenguaje a sus hijos/hijas en sus hogares a través de las tecnologías de telecomunicaciones (ej., Skype). También adaptaremos la prueba al español. Por lo tanto, estamos reclutando tanto a familias que hablen principalmente inglés en casa con sus hijos como a familias que hablen principalmente español con sus hijos.

outcome measures/ medidas de resultado
Any, age 6 to 23

An Evaluation of the Health Education Theater Course

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The purpose of this study is to see if the enrollment in a course (entitled “Health Education Theater”) causes any changes in five major outcomes. These five outcomes include: (1) the knowledge about guidelines about (a) physical activity and (b) diet/nutrition. (2) compliance to these guidelines. The third outcome is (3) the economic efficiency (e.g., return on investment (ROI)) estimated by a cost-benefit analysis (CBA)). This will account for productivity loss (e.g., income loss) saved in the long-term (e.g., life time). The fourth outcome is (4) health related quality of life. The fifth outcome is (5) self-perception well-being measures such as self-esteem and and selfefficacy.

Behavioral study
Any, age 18 years or older

Help us design better tools to manage continuous IV immunotherapy in acute lymphoblastic leukemia. Participate in a research study

We aim to understand the experiences of patients, caregivers, and nurses with continuous IV immunotherapy

The goal of this study is to learn about the experiences of patients, caregivers, and nurses with continuous IV immunotherapy. We want to understand the needs and challenges in managing continuous IV immunotherapy and how information about this therapy was provided to the patients, caregivers, and nurses. We aim to improve how we educate and support patients, family members, and nurses with this therapy in the future. We hope that the insights from this study will help us develop digital health or other tools.

Observation, workshop
Any, age 18 year or over

Improve your well-being and try a self-experimentation tool

Help us understand how self-experimentation tools can be designed to improve health and well being

Ever wonder which healthy activities are worth doing for you personally? Healthy behaviors are not one-size-fits-all. This study will test a self-guided tool called Study of Me. The tool guides you through an 30-day 'self-experiment' to figure out if a healthy activity works for you and is therefore worth doing. It uses simple self-administered healthy activity (i.e., exercise, meditation) and will be tested to see if it improves psychological well-being (i.e., happiness, stress, and focus). The purpose of this study is to evaluate the tool's design and usefulness.

At-home study
Any, age 18+

Study on Language Development in Young Adults with Fragile X Syndrome

The goal of the study is to learn more about how certain abilities (e.g. memory), certain types of experiences (e.g. interactions with family), and biology affect language abilities in adulthood for both males and females with fragile X syndrome. We are also interested in understanding how these factors and language/literacy skills affect the abilities of these young adults to function independently. Such information will help us suggest ways to improve instruction, therapy, and support to help youth fragile X to successfully transition from school to the demands of adult life.

Any, age in, entering, or just out of last year of HS

A Study Evaluating Behavioral Intervention in those at risk for Alzheimer’s Dementia

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Older adults with memory changes may eventually experience difficulty with activities of daily living (such as managing finances). This study will test an intervention for older adults who are experiencing concerns with thinking ability but do not have difficulty with managing activities of daily living. The goal of this intervention is to increase skills using a calendar system, goal setting and task list system, and organizational strategies. This intervention encourages engagement in healthy lifestyle activities such as physical exercise, intellectual stimulation, and positive emotional functioning to further promote brain health. Participants may have increased engagement in brain health activities and improved compensation strategies. All participants will have a chance to complete the intervention.

Behavioral study
Any, age 65 years or older

The Staged Treatment in Early Psychosis Study

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This study will investigate the most effective way of treating young people at risk of developing a psychotic disorder. We do not yet know what the most effective type of treatment is or the best sequence of treatments. We would like to test the effect of a sequential treatment approach for at-risk young people. This means giving them a sequence of three treatments, depending on whether the young people have a good response to each stage of treatment. The study will measure whether or not the treatment sequence was effective by: -whether the treatments improved functioning levels and psychiatric symptoms -whether or not they prevent or delay some young people transitioning to psychosis -whether they help diminish some young people’s at-risk status. The results of this study will assist with providing the best possible care in the future for young people who may be at risk of developing a psychotic disorder. It may also help us understand why some people’s symptoms and functioning get worse over time and why other people’s improve. Medications, drugs and devices have to be approved for use by the FDA. Fluoxetine is approved by the US Food and Drug Administration to treat depression. However, it is not approved to treat risk for psychosis. Therefore, its use in this study is considered to be experimental. This study will help determine if fluoxetine is an effective treatment for risk for psychosis. The research has been initiated by the study doctor, Cameron Carter, and is funded by a research grant from the US National Institute of Health (NIH).

Behavioral study, Phase 3
Any, age 12 to 25 years old