UC Davis Veterinary Clinical Trials

Understanding the genetics causing subvalvular aortic stenosis in Bullmastiffs

Help us find out what genes cause subvalvular aortic stenosis in Bullmastiffs!

Subvalvular aortic stenosis (SAS) is the second most common heart defect diagnosed in dogs, and the Bullmastiff breed is over-represented in incidence of SAS. Moderate and severely affected cases are at risk for developing severe cardiac complications, and have an average lifespan of 19 months. Furthermore, there is no surgical treatment available that results in an increased life expectancy for affected cases. The aim of this study is to identify genes/variants associated with SAS in Bullmastiffs that can be used to develop a genetic test.

Other - Genetic Study
Any, age None specified