UC Davis Veterinary Clinical Trials

Novel Treatment for Nasal Tumors

Help us treat nasal tumors in dogs using a new kind of therapy!

Nasal tumors can cause severe nasal bleeding or discharge and difficulty breathing. These tumors often aggressively spread throughout the tissues of the nasal cavity and into the surrounding organs, including the eye and brain. Radiation therapy is the treatment of choice for nasal tumors in dogs; however, radiation therapy isn't often good for long-term control of the tumor. An another treatment option is transarterial embolization, or TAE, which involves the delivery of a mechanical “clot” to the main arteries supplying blood to the tissues of the nasal cavity with the goal of eliminating the blood supply of the tumor and decreasing tumor size. The purposes of this study are to 1) describe TAE in dogs with naturally-occurring nasal cancer, 2) evaluate the effect that nasal TAE has on the tumor, and 3) evaluate the effect that nasal TAE has on the values measured by positron emission tomography (PET) scanning.

Device

Assessing a surgical treatment for dogs with hiatal hernia and/or gastroesophageal reflux

Help us learn more about this surgery to treat dogs with hiatal hernias and gastroesophageal reflux!

We believe that brachycephalic dogs have a tendency to develop hiatal herniation (HH) with greater frequency than non-brachycephalic dogs. Dogs with relative obstruction of the upper airways may generate a decreased pressure in their chest during inspiration (breathing in) that results in the upper part of the stomach being sucked into the chest (HH). This can lead to clinical signs including regurgitation, esophageal stricture formation and aspiration pneumonia if severe. We hypothesize that, if the upper airway obstruction in these dogs can be alleviated, improvement in their respiratory compromise might be seen as well as a reduction in the severity of their HH.

Device / Surgical Technique
Any, age None specified